Description
Triple Monoamine Reuptake Inhibitor · Research Grade · Metabolic Collection →
Tesofensine Research Capsules
Captide Labs Tesofensine capsules provide researchers with a precisely dosed, encapsulated format of one of the most clinically advanced investigational compounds in the field of obesity and appetite regulation research. Each capsule delivers 500mcg of Tesofensine at greater than 98% purity, independently verified by HPLC-MS analysis and documented with a full Certificate of Analysis.
Tesofensine (CAS 195875-84-4) is a triple monoamine reuptake inhibitor — blocking the reuptake of serotonin, dopamine, and norepinephrine simultaneously. Originally developed as a candidate treatment for Parkinson’s and Alzheimer’s disease, it was subsequently identified as a potent appetite suppressant and has been investigated in Phase 2 and Phase 3 clinical trials for obesity. Its unique triple-reuptake mechanism differentiates it from single or dual reuptake inhibitors and has made it a subject of significant research interest in central nervous system regulation of body weight and appetite.
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Compound
Tesofensine
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CAS Number
195875-84-4
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Molecular Formula
C₁₇H₂₃ClN₂O
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Purity
>98% (HPLC-MS Verified)
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Format
Encapsulated Powder
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Amount Per Capsule
500mcg
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Capsules Per Bottle
60
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Testing Standard
ISO 17025 Accredited Lab
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Other Ingredients
Gelatin (Vegan), Rice Flour, Silicon Dioxide
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What is Tesofensine?
Tesofensine is a pre-synaptic monoamine reuptake inhibitor that simultaneously inhibits the transporters for serotonin (SERT), dopamine (DAT), and norepinephrine (NET). This triple-reuptake mechanism elevates synaptic concentrations of all three monoamines in the central nervous system, producing a coordinated effect on appetite, satiety signaling, and energy expenditure that has been extensively studied in the context of obesity pharmacology.
Originally developed by NeuroSearch (Denmark) for Parkinson’s and Alzheimer’s disease — where monoaminergic deficits play a pathological role — Tesofensine’s potent appetite-suppressing effects were identified during clinical trials. Subsequent Phase 2 trials in obesity demonstrated among the largest weight loss effects observed for any investigational anti-obesity compound at the time, generating significant research interest in its central mechanisms of appetite and reward regulation.
Areas of active investigation
Frequently Asked Questions
For research use only. Not for human consumption, veterinary use, or food/agricultural applications. Not evaluated or approved by the FDA. Not intended to diagnose, treat, cure, or prevent any condition. All purchases are made with the understanding that this compound is strictly for in-vitro research and laboratory use.





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